胃排空的控制：迷走神经与幽门窦的相互作用。
Control of gastric emptying: interaction of the vagus and pyloric antrum.
作者信息
Yamagishi T, Debas H T
出版信息
Ann Surg. 1978 Jan;187(1):91-4. doi: 10.1097/00000658-197801000-00017.
Gastric emptying of liquids and solids was evaluated in ten dogs with gastric fistula before and after either truncal vagotomy, antrectomy, or pyloroplasty. In subsequent operations, the vagotomy group underwent either antrectomy or pyloroplasty, and the antrectomy and pyloroplasty groups were vagotomized. Vagotomy significantly inhibited the emptying of both liquids and solids (p less than 0.001) when the pyloric antrum was intact. When the antropyloric mechanism was removed by antrectomy, the effect of vagotomy was to accelerate the emptying of liquids (p less than 0.05) but to impair the emptying of solids (p less than 0.001). When the pylorus was destroyed by pyloroplasty, vagotomy markedly accelerated the emptying of liquids but had little effect on the emptying of solids. Neither antrectomy nor pyloroplasty had any significant effect on the emptying of solids. Pyloroplasty caused minor acceleration of emptying of liquids while antrectomy had no effect.
在十只患有胃瘘的狗身上，分别在进行迷走神经干切断术、胃窦切除术或幽门成形术之前及之后，对液体和固体食物的胃排空情况进行了评估。在后续手术中，迷走神经切断术组接受了胃窦切除术或幽门成形术，胃窦切除术组和幽门成形术组则进行了迷走神经切断术。当幽门窦完整时，迷走神经切断术显著抑制了液体和固体食物的排空（p小于0.001）。当通过胃窦切除术去除胃窦幽门机制时，迷走神经切断术的作用是加速液体的排空（p小于0.05），但损害固体食物的排空（p小于0.001）。当通过幽门成形术破坏幽门时，迷走神经切断术显著加速了液体的排空，但对固体食物的排空几乎没有影响。胃窦切除术和幽门成形术对固体食物的排空均无显著影响。幽门成形术导致液体排空略有加速，而胃窦切除术则没有影响。
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