Malfertheiner P, Maier W, Walliser A, Büchler M, Ditschuneit H
Z Gastroenterol. 1983 Dec;21(12):729-35.
A quantitative correlation between computer-tomographic (CT) findings and exocrine pancreatic function following secretin-ceruletide stimulation was performed in 48 patients with chronic pancreatitis; thereby a significant correlation between the degree of morphological changes in CT and the stage of functional impairment was found (r = 0,7841, p less than 0,001). Bicarbonate secretion/h showed the strongest correlation to CT findings (r = -0,7193, p less than 0,001) within the single functional parameters. CT showed a limited sensitivity (50%) in detecting chronic pancreatitis in cases with a slight functional impairment (stage 1). Morphological signs as calcifications, pancreatic duct ectasia were constantly coupled with a severe degree of functional impairment, whereas enlargement and cysts were found throughout the different functional stages.
对48例慢性胰腺炎患者进行了计算机断层扫描(CT)结果与促胰液素-蛙皮素刺激后外分泌胰腺功能之间的定量相关性研究;结果发现CT形态学改变程度与功能损害阶段之间存在显著相关性(r = 0.7841,p < 0.001)。在单个功能参数中,碳酸氢盐分泌/小时与CT结果的相关性最强(r = -0.7193,p < 0.001)。在功能损害轻微(1期)的病例中,CT检测慢性胰腺炎的敏感性有限(50%)。钙化、胰管扩张等形态学征象常与严重的功能损害相关,而肿大和囊肿则在不同功能阶段均有发现。