Ellis F H
Postgrad Med. 1984 Feb 15;75(3):139-43, 146-8. doi: 10.1080/00325481.1984.11698599.
Palliation will remain the goal of therapy for cancer of the esophagus and cardia until early diagnosis permits improvement in long-term survival rates. Of the various surgical and nonsurgical techniques available for palliation, I prefer resection with esophagogastrostomy. This procedure can now be applied to most patients, with relatively low mortality and morbidity rates. The period of treatment is short compared with the time required for other forms of therapy, and satisfactory palliation can be achieved in nearly 85% of patients, with better survival rates than for other forms of therapy. Resection is the only method of treatment that provides any reasonable hope for cure. The overall five-year survival rate in my series is 21.6%. For early stage I lesions, the five-year survival rate is 43.4%.
在早期诊断能够提高长期生存率之前,姑息治疗仍将是食管癌和贲门癌治疗的目标。在可用于姑息治疗的各种手术和非手术技术中,我更倾向于食管胃吻合术切除。现在该手术可应用于大多数患者,死亡率和发病率相对较低。与其他治疗方式所需时间相比,治疗周期较短,近85%的患者可实现满意的姑息治疗,生存率高于其他治疗方式。切除是唯一有望实现治愈的治疗方法。在我的系列病例中,总体五年生存率为21.6%。对于早期I期病变,五年生存率为43.4%。