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食管癌胃切除术治疗癌症:当前的医院死亡率和发病率

Esophagogastrectomy for carcinoma: current hospital mortality and morbidity rates.

作者信息

Ellis F H, Gibb S P

出版信息

Ann Surg. 1979 Dec;190(6):699-705. doi: 10.1097/00000658-197912000-00005.

Abstract

Between January 1, 1970, and March 1, 1979, 153 patients with carcinoma of the esophagus or cardia were seen at the Lahey Clinic; 124 (81%) underwent surgical exploration and 102 (82.3%) were found amendable to resection. This report concerns the 82 patients operated on by the senior author, 72 of whom (87.8%) had surgical resection. A variety of resective techniques were used but currently esophagogastrectomy and esophagogastrostomy is preferred, a left thoracotomy being used for low lying lesions; upper thoracic and cervical lesions are approached through a combined abdominal and right thoracic approach or esophagectomy with cervical esophagogastrostomy and without thoracotomy is used. Two deaths occurred within 30 days of operation, a hospital mortality rate of 2.8%. Significant complications developed in 11 patients (15.3%). The average survival was 20.8 months, and satisfactory long-term relief of dysphagia was achieved in 91.2% of patients. An aggressive surgical approach to the management of patients with carcinoma of the esophagus or cardia is justified, for esophagogastrectomy and esophagogastrostomy is applicable to the majority of patients; can now be performed at low risk with a reasonable period of hospitalization; and provides satisfactory long-term palliation.

摘要

1970年1月1日至1979年3月1日期间,拉希诊所共诊治了153例食管癌或贲门癌患者;其中124例(81%)接受了手术探查,102例(82.3%)被认为适合切除。本报告涉及由资深作者实施手术的82例患者,其中72例(87.8%)接受了手术切除。采用了多种切除技术,但目前首选食管胃切除术和食管胃吻合术,低位病变采用左胸切口;上胸部和颈部病变通过腹部和右胸联合切口处理,或采用食管切除术加颈部食管胃吻合术且不进行开胸手术。术后30天内发生2例死亡,医院死亡率为2.8%。11例患者(15.3%)出现了严重并发症。平均生存期为20.8个月,91.2%的患者吞咽困难得到了满意的长期缓解。对于食管癌或贲门癌患者,积极的手术治疗方法是合理的,因为食管胃切除术和食管胃吻合术适用于大多数患者;现在可以在低风险下进行,住院时间合理;并且能提供满意的长期姑息治疗。

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