Knight C H, Docherty A H, Peaker M
J Dairy Res. 1984 Feb;51(1):29-35. doi: 10.1017/s0022029900023293.
An attempt was made to partition changes in milk yield during lactation in the rat between changes in the size of the secretory cell population and changes in cellular activity. Groups of rats were studied on d 2, 7, 14, 21 and 28 of lactation. Milk yield increased between d 2 and 7, less markedly between d 7 and 14 and decreased between d 14 and 21. Milk secretion had apparently ceased on d 28. Total mammary DNA (DNAt) and RNA (RNAt) increased from d 2 to 14. It is concluded that of the increase in milk yield between d 2 and 14, an increase in cell population accounted for 75% and an increase in cellular activity for 25%. A decrease in activity appeared to be entirely responsible for the decrease in yield between d 14 and 21.
研究人员试图将大鼠哺乳期产奶量的变化，在分泌细胞群体大小的变化和细胞活性的变化之间进行划分。在哺乳期的第2、7、14、21和28天对几组大鼠进行了研究。产奶量在第2天至第7天之间增加，在第7天至第14天之间增加不太明显，在第14天至第21天之间减少。在第28天，乳汁分泌显然已经停止。乳腺总DNA（DNAt）和RNA（RNAt）从第2天到第14天增加。得出的结论是，在第2天至第14天产奶量的增加中，细胞群体的增加占75%，细胞活性的增加占25%。活性的降低似乎完全是第14天至第21天产奶量下降的原因。
