同基因肿瘤细胞毒性T细胞的Ly表型
Ly phenotype of cytotoxic T cells for syngeneic tumor.
作者信息
Shiku H, Takahashi T, Bean M A, Old L J, Oettgen H F
出版信息
J Exp Med. 1976 Oct 1;144(4):1116-20. doi: 10.1084/jem.144.4.1116.
Abstract
Our present and previous findings may be summarized as follows: The phenotype of C57BL/6 (B6) cytotoxic cells for allogeneic target cells is Thy-1+, Ly-1- Ly-2/3+, MSLA+, and Ig-. the phenotype of B6 cytotoxic cells for syngeneic tumor cells is Thy-1+, Ly-1+, Ly-2/3+, MSLA+, and Ig-. The phenotype of B6 cytotoxic cells for syngeneic tumor cells is Thy-1+, Ly-1+, Ly-2/3+, MSLA+, AND Ig-. Thus, differences in Ly phenotype appear to be exhibited not only by cytotoxic T cells as opposed to helper T cells, but also within subcategories of cytotoxic T cells.
摘要
我们目前和先前的研究结果可总结如下
C57BL/6（B6）对同种异体靶细胞的细胞毒性细胞表型为Thy-1+、Ly-1-、Ly-2/3+、MSLA+和Ig-。B6对同基因肿瘤细胞的细胞毒性细胞表型为Thy-1+、Ly-1+、Ly-2/3+、MSLA+和Ig-。B6对同基因肿瘤细胞的细胞毒性细胞表型为Thy-1+、Ly-1+、Ly-2/3+、MSLA+和Ig-。因此，Ly表型的差异似乎不仅在细胞毒性T细胞与辅助性T细胞之间表现出来，而且在细胞毒性T细胞的亚类中也有表现。
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