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电休克治疗对血清髓鞘碱性蛋白免疫反应性的影响。

Effect of electroconvulsive therapy on serum myelin basic protein immunoreactivity.

作者信息

Hoyle N R, Pratt R T, Thomas D G

出版信息

Br Med J (Clin Res Ed). 1984 Apr 14;288(6424):1110-1. doi: 10.1136/bmj.288.6424.1110.

Abstract

A sensitive radioimmunoassay that can detect brain damage in cases of head injury and stroke was applied to blood samples from 13 patients before and after they received multiple treatments with electroconvulsive therapy for psychiatric disorder. None of the patients showed a significant increase in serum myelin basic protein immunoreactivity. As increased serum myelin basic protein immunoreactivity may reflect myelin damage it is apparent that in these patients electroconvulsive therapy did not cause measureable breakdown of myelin.

摘要

一种能检测头部受伤和中风病例中脑损伤的灵敏放射免疫测定法,被应用于13名因精神障碍接受多次电休克治疗前后的患者的血样检测。没有一名患者的血清髓磷脂碱性蛋白免疫反应性出现显著增加。由于血清髓磷脂碱性蛋白免疫反应性增加可能反映髓磷脂损伤,显然在这些患者中,电休克治疗并未导致可测量的髓磷脂分解。

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