神经外科患者血清中的髓鞘碱性蛋白免疫反应性
Myelin basic protein immunoreactivity in serum of neurosurgical patients.
作者信息
Thomas D G, Hoyle N R, Seeldrayers P
出版信息
J Neurol Neurosurg Psychiatry. 1984 Feb;47(2):173-5. doi: 10.1136/jnnp.47.2.173.
Abstract
Patients admitted to the neurosurgical wards for the management of nervous system tumours, subarachnoid and intracerebral haemorrhage, head injury, spinal and peripheral nerve lesions, and other miscellaneous neurosurgical conditions, were studied by assay of serum immunoreactivity for myelin basic protein. Of 171 patients, 70% proved to have elevated myelin basic protein activity. In cerebral cases the extent of brain damage assessed by clinical methods appeared to correlate with the appearance of elevated serum myelin basic protein. In spinal and peripheral nerve cases no similar elevation of myelin basic protein was observed.
摘要
对入住神经外科病房以治疗神经系统肿瘤、蛛网膜下腔和脑内出血、头部损伤、脊髓和周围神经病变以及其他各种神经外科病症的患者，通过检测血清髓鞘碱性蛋白免疫反应性进行了研究。在171名患者中，70% 的患者血清髓鞘碱性蛋白活性升高。在脑部病例中，通过临床方法评估的脑损伤程度似乎与血清髓鞘碱性蛋白升高的情况相关。在脊髓和周围神经病例中，未观察到类似的髓鞘碱性蛋白升高现象。
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