Vaage J
Cancer Res. 1984 May;44(5):1876-9.
The occurrence of shared nonviral tumor-associated antigens among 18 immunogenic C3H/He mammary carcinomas was investigated in vivo. By cross-immunization and s.c. challenge between pairs of tumors in 37 different combinations, six of the tumors were found to cross-immunize with one to three other tumors. A minimum of three different antigenic specificities were found to be shared among cross-reacting tumors.
对18种具有免疫原性的C3H/He乳腺癌中共享的非病毒肿瘤相关抗原的发生情况进行了体内研究。通过37种不同组合的肿瘤对之间的交叉免疫和皮下攻击,发现其中6种肿瘤可与一至三种其他肿瘤发生交叉免疫。在交叉反应的肿瘤中发现至少共有三种不同的抗原特异性。