鸡大脑和肝脏中的DNA甲基化
DNA methylation in chicken brain and liver.
作者信息
Harasawa R, Mitsuoka T
出版信息
Experientia. 1984 Apr 15;40(4):390-2. doi: 10.1007/BF01952569.
PMID:6201388
Abstract
Adult chicken brain DNA is subject to a developmental alteration of methylation at HpaII sites flanking 4, 1, 0.8 and 0.7 kilobase sequences. This change is not evident in adult chicken liver DNA and 1-day-old chick brain and liver DNAs, suggesting tissue specificity and age-dependency in DNA methylation.
摘要
成年鸡脑DNA在侧翼为4、1、0.8和0.7千碱基序列的HpaII位点会发生甲基化的发育性改变。这种变化在成年鸡肝DNA以及1日龄雏鸡的脑和肝DNA中并不明显，这表明DNA甲基化存在组织特异性和年龄依赖性。
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