Dawson J F, Brochier J, Schmitt D, Saeland S, Thivolet J
Br J Dermatol. 1984 May;110(5):539-46. doi: 10.1111/j.1365-2133.1984.tb04676.x.
HB8 is a new monoclonal antibody, prepared against human lymphocytes, which has been found to react with elastic fibres, possibly the microfibrillar component. Samples of normal human and animal skin and human skin from various pathological conditions were subjected to immunolabelling with HB8, and alternate sections from each sample were stained by a standard orcein procedure. The individual fibres were clearly marked by the HB8 and this was confirmed by comparison with the standard elastic tissue stain. HB8 provides a new direct, practical and accurate method for the study of elastic tissue.
HB8是一种新的单克隆抗体，它是针对人类淋巴细胞制备的，已发现它能与弹性纤维发生反应，可能是与微原纤维成分发生反应。对正常人皮肤和动物皮肤样本以及来自各种病理状况的人类皮肤样本用HB8进行免疫标记，并对每个样本的交替切片采用标准的地衣红染色法进行染色。HB8能清晰地标记出单个纤维，通过与标准弹性组织染色法对比得以证实。HB8为弹性组织的研究提供了一种新的直接、实用且准确的方法。
