Aguila L A, Chou S M, Bay J W
Neurosurgery. 1984 Apr;14(4):475-9.
Primary intracranial germinomas are classically known as midline lesions, occurring most commonly in the pineal and suprasellar regions, and will usually present with symptoms related to increased intracranial pressure or hypothalmic dysfunction. Involvement of both the pineal and the suprasellar region in the same patient (double midline lesions) is relatively rare (7%). Dissemination of germinoma to both cerebellopontine angles, in addition to the double midline lesions, with the initial clinical presentation of lower cranial nerve involvement has not been previously reported. We encountered such an unusual case, which prompted this report and review of the literature.
原发性颅内生殖细胞瘤通常被认为是中线病变,最常见于松果体区和鞍上区,通常会出现与颅内压升高或下丘脑功能障碍相关的症状。同一患者的松果体区和鞍上区均受累(双中线病变)相对少见(7%)。除双中线病变外,生殖细胞瘤扩散至双侧桥小脑角,且最初临床表现为低位颅神经受累,此前尚未见报道。我们遇到了这样一例罕见病例,因此撰写本报告并复习相关文献。