Clemmensen O J, Staberg B, Worm A M
Acta Derm Venereol. 1984;64(1):5-8.
Suction blister fluid from the abdominal skin of 14 healthy subjects was examined for the presence of split products of complement C3 (C3-split) as an indicator of complement activation before and after treatment with either UVA or PUVA. Following PUVA a significant increase in C3-split was found (p less than 0.05) in both irradiated and non-irradiated skin areas. Following UVA the increase in C3-split was less pronounced. The activation of complement may play an important role in the maintenance of the delayed erythema that appears after irradiation with long-wave ultraviolet light.
检测了14名健康受试者腹部皮肤的抽吸水疱液中补体C3裂解产物（C3裂解）的存在情况，以此作为补体激活的指标，观察其在接受紫外线A（UVA）或补骨脂素加紫外线A（PUVA）治疗前后的变化。接受PUVA治疗后，在照射和未照射的皮肤区域均发现C3裂解显著增加（p小于0.05）。接受UVA治疗后，C3裂解的增加则不太明显。补体激活可能在长波紫外线照射后出现的延迟红斑的维持中起重要作用。
