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阿片类拮抗剂纳洛酮对实验性瘙痒的影响。

The influence of the opiate antagonist naloxone on experimental pruritus.

作者信息

Fjellner B, Hägermark O

出版信息

Acta Derm Venereol. 1984;64(1):73-5.

PMID:6203288
Abstract

The antipruritic effect of naloxone hydrochloride was evaluated in a double-blind, cross-over design. Systemic pretreatment with the opiate antagonist did not interfere with the cutaneous itch and flare responses evoked by morphine or histamine, nor did it inhibit the morphine-produced potentiation of the histamine-elicited skin reactions.

摘要

采用双盲交叉设计评估了盐酸纳洛酮的止痒效果。用阿片类拮抗剂进行全身预处理并不干扰吗啡或组胺引起的皮肤瘙痒和潮红反应，也不抑制吗啡对组胺引起的皮肤反应的增强作用。

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引用本文的文献

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