Hizawa K, Inaba H, Nakanishi S, Otsuka H, Izumi K
Am J Surg Pathol. 1984 May;8(5):393-8. doi: 10.1097/00000478-198405000-00008.
A 77-year-old man developed an induration of the buttock following repeated injections of an antihypertensive remedy containing polyvinylpyrrolidone (PVP). The excised tumor had a cellular, pseudosarcomatous appearance with abundant extracellular material, and resembled a myxoid liposarcoma. All of the staining reactions and infra-red spectrophotometry of the deposition indicated the presence of PVP. The awareness of such a cellular PVP granuloma is important for surgical pathologists so as to avoid the diagnosis of sarcoma.
一名77岁男性在反复注射含有聚乙烯吡咯烷酮（PVP）的抗高血压药物后，臀部出现硬结。切除的肿瘤具有细胞性、假肉瘤样外观，伴有丰富的细胞外物质，类似于黏液样脂肪肉瘤。沉积物的所有染色反应和红外分光光度法均表明存在PVP。认识到这种细胞性PVP肉芽肿对手术病理学家很重要，以避免误诊为肉瘤。
