Nisselbaum J S, Bosl G J, Golbey R B, Schwartz D C, Schwartz M K
Ann Clin Lab Sci. 1984 May-Jun;14(3):179-88.
The usefulness of measuring both alpha-fetoprotein and hCG in following the progress of patients with testicular cancers and germ cell tumors is demonstrated. In almost half the cases of testicular cancers studied, only one tumor marker was elevated; in at least one instance, the source of alpha-fetoprotein was eliminated while the source of hCG persisted. A comparison of the hCG method in use at Memorial Sloan-Kettering Cancer Center ( MSKCC ) with a commercial kit (Corning) showed that the methods were equivalent for monitoring both testicular cancers and gestational trophoblastic disease. All 17 patients with hepatocellular carcinoma had elevated levels of alpha-fetoprotein.
已证实，在监测睾丸癌和生殖细胞肿瘤患者的病情进展时，同时检测甲胎蛋白和人绒毛膜促性腺激素是有用的。在所研究的睾丸癌病例中，几乎有一半病例只有一种肿瘤标志物升高；至少有一个病例，甲胎蛋白的来源已消除，而人绒毛膜促性腺激素的来源依然存在。将纪念斯隆-凯特琳癌症中心（MSKCC）使用的人绒毛膜促性腺激素检测方法与一种商用试剂盒（康宁公司）进行比较，结果表明这两种方法在监测睾丸癌和妊娠滋养细胞疾病方面效果相当。所有17例肝细胞癌患者的甲胎蛋白水平均升高。
