Katoh Y, Kanematsu M, Shimizu N
No To Shinkei. 1984 Feb;36(2):185-91.
In an attempt to give some contribution to the morphology of locus coeruleus (LC) in the ddY mouse (weighing about 20 g), we made light-microscopic investigations using several staining methods in normal condition. First, we studied the cytoarchitectonics and cell numbers of LC by the Klüver-Barrera method and amine demonstrating wet fluorescent method. LC of the mouse measured 600 +/- 60 micrometers in antero-posterior extent in the dorso-lateral tegmental area. At the rostral part of LC small number of constituent cells were disseminated, the middle part (principal part) showing the triangle-shaped cell accumulation with an apex directing to the IV ventricle. The caudal part forming small accumulation of cells ended directly beneath the IV ventricle. Number of unilateral LC cells amounted to 1250 +/- 92 by Klüver-Barrera method, while 1326 +/- 44 by the wet fluorescent method. The LC was cytoarchitectonically divided into the dorsal and ventral parts. The cell size of the dorsal part averaged (16.2 +/- 2.8) x (25.5 +/- 4.6) micrometers along the longest and shortest axes, while that of ventral part (17.3 +/- 3.1) x (30.2 +/- 5.6) micrometers.
为了对ddY小鼠（体重约20克）蓝斑（LC）的形态学做出一些贡献，我们在正常条件下使用几种染色方法进行了光学显微镜研究。首先，我们通过Klüver-Barrera法和胺显示湿荧光法研究了LC的细胞构筑和细胞数量。小鼠的LC在背外侧被盖区的前后长度为600±60微米。在LC的头端部分，有少量组成细胞散布，中间部分（主要部分）呈现三角形细胞聚集，其尖端指向第四脑室。尾端部分形成小的细胞聚集，直接在第四脑室下方结束。通过Klüver-Barrera法，单侧LC细胞数量为1250±92个，而通过湿荧光法为1326±44个。LC在细胞构筑上分为背侧和腹侧部分。背侧部分细胞大小沿最长和最短轴平均为（16.2±2.8）×（25.5±4.6）微米，而腹侧部分为（17.3±3.1）×（30.2±5.6）微米。
