路/ c大鼠体内天然存在的抗干扰素抗体。
Naturally occurring anti-interferon antibodies in Lou/c rats.
作者信息
De Maeyer-Guignard J, Cachard-Thomas A, De Maeyer E
出版信息
J Immunol. 1984 Aug;133(2):775-8.
PMID:6203979
Abstract
Rats of the Lou/c strain have natural antibodies with binding and neutralizing activity against mouse and rat interferon. The antibodies can be purified on a column of goat IgG directed against rat IgG, and they have an affinity for protein A-Sepharose. They are already present in very young (2-wk-old) animals, and the titers increase with increasing age.
摘要
Lou/c品系的大鼠具有针对小鼠和大鼠干扰素的具有结合和中和活性的天然抗体。这些抗体可在针对大鼠IgG的山羊IgG柱上纯化，并且它们对蛋白A-琼脂糖有亲和力。它们在非常年幼（2周龄）的动物中就已存在，并且效价随年龄增长而增加。
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