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主动脉缩窄行锁骨下动脉瓣主动脉成形术的组织解剖学背景

Histo-anatomical backgrounds of subclavian flap aortoplasty in coarctation of the aorta.

作者信息

van Meurs-van Woezik H, Debets T, Klein H W, Krediet P

出版信息

Thorac Cardiovasc Surg. 1984 Apr;32(2):72-7. doi: 10.1055/s-2007-1023351.

Abstract

After repair of coarctation of the aorta using the technique of resection and end-to-end anastomosis, the internal diameters of the aortic isthmus and descending aorta often fail to increase. Better results seem possible with aortoplasty using the left subclavian flap technique. In order to clarify this matter, we investigated the structure of the left subclavian artery comparing it with that of the descending aorta and aortic isthmus: we studied the internal diameter, the thickness of the tunica media and the packing density of its elastic fibers in these vascular elements using a postmortem material of children with a coarctation of the aorta. The ages ranged from 4 days to 13 months with one child of 8 years. All 16 cases had one or more additional cardiac lesions. Operation had been performed in 3 children: 2 end-to-end anastomoses and one subclavian bypass of the aortic arch. Data were compared with observations on autopsy cases of children without cardiovascular abnormalities. The mean findings were that the calibers of the left subclavian artery and the descending aorta were within normal limits but that the caliber of the aortic isthmus was smaller than in normal children. The measurements on the tunica media showed that although, generally, the thickness of the media of the left subclavian artery was smaller than that of the aortic isthmus and descending aorta of the same individual, it contained relatively more elastic fibers than the matching vessels. This may indicate that the structure of the left subclavian artery is well suited to grow out as a part of the aortic arch.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在采用切除及端端吻合技术修复主动脉缩窄后,主动脉峡部和降主动脉的内径往往无法增大。采用左锁骨下动脉瓣技术进行主动脉成形术可能会取得更好的效果。为了阐明这一问题,我们对左锁骨下动脉的结构进行了研究,并将其与降主动脉和主动脉峡部的结构进行比较:我们使用患有主动脉缩窄的儿童尸检材料,研究了这些血管结构的内径、中膜厚度及其弹性纤维的堆积密度。年龄范围从4天至13个月,其中有一名8岁儿童。所有16例均有一个或多个其他心脏病变。3名儿童接受了手术:2例行端端吻合术,1例行主动脉弓锁骨下动脉旁路术。将数据与无心血管异常的儿童尸检病例的观察结果进行比较。平均结果显示,左锁骨下动脉和降主动脉的管径在正常范围内,但主动脉峡部的管径小于正常儿童。对中膜的测量表明,虽然一般来说,同一个体的左锁骨下动脉中膜厚度小于主动脉峡部和降主动脉,但与相应血管相比,其弹性纤维相对较多。这可能表明左锁骨下动脉的结构非常适合作为主动脉弓的一部分向外生长。(摘要截断于250字)

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