Kamme C, Soltesz V, Sundbärg G
J Hosp Infect. 1984 Jun;5(2):147-54. doi: 10.1016/0195-6701(84)90118-x.
Fourteen of 80 patients (17.5 per cent) who underwent elective craniotomy preceded by a strict pre-operative routine of skin decontamination contracted postoperative wound infection. Most of the infections were probably from endogenous sources and from eight of the wounds low-virulent resident skin bacteria, Propionibacterium acnes and/or Staphylococcus epidermidis, were isolated. Since thorough pre-operative preparation of the skin did not reduce the incidence of infection to an acceptable level, antibiotic prophylaxis might be indicated in this type of surgery.
80例接受择期开颅手术的患者中，有14例（17.5%）在术前严格进行皮肤消毒后仍发生了术后伤口感染。大多数感染可能源于内源性，并且在8个伤口中分离出了低毒力的常驻皮肤细菌痤疮丙酸杆菌和/或表皮葡萄球菌。由于术前对皮肤的彻底准备并未将感染发生率降低到可接受的水平，因此在这类手术中可能需要预防性使用抗生素。
