Pawar K R, Katdare M
Toxicol Lett. 1984 Jul;22(1):7-13. doi: 10.1016/0378-4274(84)90038-9.
The toxic and teratogenic effects of fenitrothion, benzene hexachloride (BHC) and carbofuran on the embryos and tadpoles of the frog Microhyla ornata were investigated for a period of 96 h. Of the three pesticides tested, fenitrothion was found to be most toxic and teratogenic and carbofuran the least toxic while BHC was intermediate. Tadpoles were observed to be more sensitive than the embryos to these pesticides. Abnormalities observed in embryos and tadpoles were the occurrence of blisters on the body, distention of body cavities, curvature of the body axis, poor blood circulation, poor pigmentation, retarded growth, loss of balance and abnormal behaviour.
研究了杀螟硫磷、六六六(BHC)和克百威对饰纹姬蛙胚胎和蝌蚪96小时的毒性和致畸作用。在所测试的三种农药中,杀螟硫磷的毒性和致畸性最强,克百威毒性最小,六六六居中。观察到蝌蚪比胚胎对这些农药更敏感。在胚胎和蝌蚪中观察到的异常包括身体出现水泡、体腔扩张、身体轴弯曲、血液循环不良、色素沉着不良、生长迟缓、失去平衡和行为异常。