Matter J, Andersen E, Cimasoni G
J Biol Buccale. 1984 Jun;12(2):133-43.
Most of the previous histological studies devoted to free gingival grafts in humans were limited to the description of the various phases of healing between the graft and the subjacent tissues. The present long-term study illustrates the histological findings 1 to 36 months after grafting along the zone of passage between graft and surrounding tissues. In the transitional zone between graft and alveolar mucosa it was found that the structural characteristics of the palatal mucosa, with its dense network of collagen fibres and its orthokeratinized superficial layer were conserved even after an interval of time as long as 16 months. These features contrasted with the loose network of collagen fibres and the presence of numerous elastic fibres in the alveolar mucosa. As for the transitional zone between graft and gingiva the findings confirmed that these two types of mucosa are similar, except that the gingival epithelium showed, in epon embedded sections, a layer of parakeratinization, as opposed to the dense layer of orthokeratin found on the grafted palatal epithelium. A constant feature in the present investigation was the change in orientation of the collagen fibres along the zones of healing, both between graft and alveolar mucosa and between graft and gingiva.
先前大多数针对人类游离龈瓣移植的组织学研究，都局限于描述移植瓣与下方组织愈合的各个阶段。本长期研究阐述了移植后1至36个月沿移植瓣与周围组织移行区域的组织学发现。在移植瓣与牙槽黏膜的过渡区，发现即使经过长达16个月的时间间隔，腭黏膜致密的胶原纤维网络及其正角化表层的结构特征仍得以保留。这些特征与牙槽黏膜中疏松的胶原纤维网络及大量弹性纤维的存在形成对比。至于移植瓣与牙龈之间的过渡区，研究结果证实这两种黏膜相似，只是在环氧树脂包埋切片中，牙龈上皮显示有一层不全角化，与移植的腭上皮上发现的致密正角化层不同。本研究中的一个恒定特征是，沿愈合区域，无论是在移植瓣与牙槽黏膜之间还是在移植瓣与牙龈之间，胶原纤维的方向都发生了变化。
