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利用针对主要病毒特异性多肽的单克隆抗体对马立克氏病病毒和火鸡疱疹病毒之间血清学交叉反应的研究。简报

Studies on the serological cross-reaction between Marek's disease virus and herpesvirus of turkeys using monoclonal antibodies to major virus-specific polypeptides. Brief report.

作者信息

Ikuta K, Nakajima K, Ueda S, Kato S, Hirai K

出版信息

Arch Virol. 1984;81(3-4):337-43. doi: 10.1007/BF01310004.

DOI:10.1007/BF01310004
PMID:6206826
Abstract

A major virus-specific polypeptide antigenically cross-reactive between Marek's disease virus (MDV) and herpesvirus of turkeys (HVT) was characterized by two monoclonal antibodies against MDV. The antigenic determinant recognized by one monoclonal antibody was present only in the MDV polypeptide but not in the HVT polypeptide, whereas the antigenic determinant recognized by the other antibody was present in both MDV and HVT polypeptides. Peptide mapping showed the difference in the amino acid sequence of the two polypeptides.

摘要

用两种抗马立克氏病病毒（MDV）的单克隆抗体鉴定了一种在马立克氏病病毒（MDV）和火鸡疱疹病毒（HVT）之间具有抗原交叉反应性的主要病毒特异性多肽。一种单克隆抗体识别的抗原决定簇仅存在于MDV多肽中，而不存在于HVT多肽中，而另一种抗体识别的抗原决定簇则同时存在于MDV和HVT多肽中。肽图谱显示了两种多肽氨基酸序列的差异。

相似文献

1
Studies on the serological cross-reaction between Marek's disease virus and herpesvirus of turkeys using monoclonal antibodies to major virus-specific polypeptides. Brief report.利用针对主要病毒特异性多肽的单克隆抗体对马立克氏病病毒和火鸡疱疹病毒之间血清学交叉反应的研究。简报
Arch Virol. 1984;81(3-4):337-43. doi: 10.1007/BF01310004.
2
Monoclonal antibodies specific to and cross-reactive with Marek's disease virus and herpesvirus of turkeys.对马立克氏病病毒和火鸡疱疹病毒具有特异性且交叉反应的单克隆抗体。
Biken J. 1982 Dec;25(4):171-5.
3
Most virus-specific polypeptides in cells productively infected with Marek's disease virus or herpesvirus of turkeys possess cross-reactive determinants.在被马立克氏病病毒或火鸡疱疹病毒有效感染的细胞中，大多数病毒特异性多肽具有交叉反应性决定簇。
J Gen Virol. 1983 Apr;64 (Pt 4):961-5. doi: 10.1099/0022-1317-64-4-961.
4
Monoclonal antibodies reactive with the surface and secreted glycoproteins of Marek's disease virus and herpesvirus of turkeys.与马立克氏病病毒和火鸡疱疹病毒的表面及分泌糖蛋白发生反应的单克隆抗体。
J Gen Virol. 1983 Dec;64 ( Pt 12):2597-610. doi: 10.1099/0022-1317-64-12-2597.
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Processing of glycoprotein gB related to neutralization of Marek's disease virus and herpesvirus of turkeys.与马立克氏病病毒和火鸡疱疹病毒中和作用相关的糖蛋白gB的加工过程。
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Antigen B of the vaccine strains of Marek's disease virus and herpesvirus of turkeys presents heat-labile group and serotype specific epitopes.马立克氏病病毒和火鸡疱疹病毒疫苗株的抗原B呈现热不稳定的群特异性和血清型特异性表位。
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Characterization of the gene encoding herpesvirus of turkeys gp57-65: comparison to Marek's disease virus gp57-65 and herpes simplex virus glycoprotein C.火鸡疱疹病毒gp57-65编码基因的特性：与马立克氏病病毒gp57-65及单纯疱疹病毒糖蛋白C的比较
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引用本文的文献

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Establishment of a variant type of turkey herpesvirus which releases cell-free virus into the culture medium in large quantities. Brief report.一种能大量向培养基中释放无细胞病毒的火鸡疱疹病毒变异株的建立。简报。
Arch Virol. 1986;91(1-2):183-92. doi: 10.1007/BF01316738.
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Identification with monoclonal antibodies of virus-specific DNA-binding proteins in the nuclei of cells infected with three serotypes of Marek's disease virus-related viruses.用单克隆抗体鉴定感染三种马立克氏病病毒相关病毒血清型的细胞细胞核中病毒特异性DNA结合蛋白。
J Virol. 1986 Jul;59(1):154-8. doi: 10.1128/JVI.59.1.154-158.1986.
3
Similarities and dissimilarities in the structure and expression of viral genomes of various virus strains immunologically related to Marek's disease virus.

本文引用的文献

1
Identification with monoclonal antibodies of glycoproteins of Marek's disease virus and herpesvirus of turkeys related to virus neutralization.用单克隆抗体鉴定与病毒中和相关的马立克氏病病毒和火鸡疱疹病毒糖蛋白。
J Virol. 1984 Mar;49(3):1014-7. doi: 10.1128/JVI.49.3.1014-1017.1984.
2
Molecular-biological characterization of Marek's disease virus. II. Differentiation of various MDV and HVT strains.马立克氏病病毒的分子生物学特性。II. 各种马立克氏病病毒和火鸡疱疹病毒毒株的鉴别
Virology. 1982 Aug;121(1):133-46. doi: 10.1016/0042-6822(82)90123-4.
3
Immunoprecipitation of Marek's disease virus-specific polypeptides with chicken antibodies purified by affinity chromatography.
与马立克氏病病毒免疫相关的各种病毒株的病毒基因组在结构和表达上的异同。
Arch Virol. 1986;89(1-4):113-30. doi: 10.1007/BF01309883.
4
Identification of viral proteins encoded by two DNA fragments of herpesvirus of turkeys (HVT).火鸡疱疹病毒（HVT）两个DNA片段编码的病毒蛋白的鉴定
Virus Genes. 1991 Jul;5(3):227-33. doi: 10.1007/BF00568972.
用亲和层析纯化的鸡抗体对马立克氏病病毒特异性多肽进行免疫沉淀。
Virology. 1981 Oct 15;114(1):277-81. doi: 10.1016/0042-6822(81)90277-4.
4
Monoclonal antibodies reactive with the surface and secreted glycoproteins of Marek's disease virus and herpesvirus of turkeys.与马立克氏病病毒和火鸡疱疹病毒的表面及分泌糖蛋白发生反应的单克隆抗体。
J Gen Virol. 1983 Dec;64 ( Pt 12):2597-610. doi: 10.1099/0022-1317-64-12-2597.
5
Monoclonal antibodies specific to and cross-reactive with Marek's disease virus and herpesvirus of turkeys.对马立克氏病病毒和火鸡疱疹病毒具有特异性且交叉反应的单克隆抗体。
Biken J. 1982 Dec;25(4):171-5.
6
Most virus-specific polypeptides in cells productively infected with Marek's disease virus or herpesvirus of turkeys possess cross-reactive determinants.在被马立克氏病病毒或火鸡疱疹病毒有效感染的细胞中，大多数病毒特异性多肽具有交叉反应性决定簇。
J Gen Virol. 1983 Apr;64 (Pt 4):961-5. doi: 10.1099/0022-1317-64-4-961.
7
Monoclonal antibodies to the glycoprotein of vesicular stomatitis virus: comparative neutralizing activity.针对水疱性口炎病毒糖蛋白的单克隆抗体：比较中和活性。
J Virol. 1982 Apr;42(1):220-7. doi: 10.1128/JVI.42.1.220-227.1982.
8
Evaluation of DNA homology of Marek's disease virus, herpesvirus of turkeys and Epstein-Barr virus under varied stringent hybridization conditions.在不同严格杂交条件下对马立克氏病病毒、火鸡疱疹病毒和爱泼斯坦-巴尔病毒的DNA同源性评估。
J Biochem. 1984 Apr;95(4):1215-8. doi: 10.1093/oxfordjournals.jbchem.a134712.
9
Isolation from turkeys of a cell-associated herpesvirus antigenically related to Marek's disease virus.从火鸡中分离出一种与马立克氏病病毒抗原相关的细胞相关疱疹病毒。
Am J Vet Res. 1970 Mar;31(3):525-38.
10
Use of staphylococcal protein A as an immunological reagent.葡萄球菌蛋白A作为一种免疫试剂的应用。
J Immunol Methods. 1978;20:241-53. doi: 10.1016/0022-1759(78)90259-4.