用单克隆抗体鉴定与病毒中和相关的马立克氏病病毒和火鸡疱疹病毒糖蛋白。
Identification with monoclonal antibodies of glycoproteins of Marek's disease virus and herpesvirus of turkeys related to virus neutralization.
作者信息
Ikuta K, Ueda S, Kato S, Hirai K
出版信息
J Virol. 1984 Mar;49(3):1014-7. doi: 10.1128/JVI.49.3.1014-1017.1984.
Abstract
By use of monoclonal antibodies cross-reactive with Marek's disease virus and herpesvirus of turkeys, three glycoproteins (for Marek's disease virus, gp115/110, gp63, and gp50; for herpesvirus of turkeys, gp115, gp62 and gp52) related to virus neutralization were identified. Immunization of chickens or rabbits with these glycoproteins purified by affinity chromatography resulted in production of neutralizing antibodies.
摘要
通过使用与马立克氏病病毒和火鸡疱疹病毒交叉反应的单克隆抗体，鉴定出三种与病毒中和相关的糖蛋白（对于马立克氏病病毒，为gp115/110、gp63和gp50；对于火鸡疱疹病毒，为gp115、gp62和gp52）。用通过亲和层析纯化的这些糖蛋白对鸡或兔进行免疫，可产生中和抗体。
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