• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

在不同严格杂交条件下对马立克氏病病毒、火鸡疱疹病毒和爱泼斯坦-巴尔病毒的DNA同源性评估。

Evaluation of DNA homology of Marek's disease virus, herpesvirus of turkeys and Epstein-Barr virus under varied stringent hybridization conditions.

作者信息

Hirai K, Ikuta K, Maotani K, Kato S

出版信息

J Biochem. 1984 Apr;95(4):1215-8. doi: 10.1093/oxfordjournals.jbchem.a134712.

DOI:10.1093/oxfordjournals.jbchem.a134712
PMID:6086596
Abstract

Marek's disease virus (MDV) showed only 0.3-0.6% homology in DNA sequence with herpesvirus of turkeys (HVT) at Tm-24.4 degrees C in spite of its antigenic similarity to the latter. Southern blot hybridization under stringent conditions showed that the homology between MDV and HVT is located in the restricted portion of these viral genomes. At Tm-49.6 degrees C, which permits the detection of homology with one base mismatch in three between the MDV and HVT DNAs, sequences with weak homology were found to be distributed over most of these viral genomes. No homology was detected between Epstein-Barr virus and either MDV or HVT DNA.

摘要

马立克氏病病毒（MDV）尽管与火鸡疱疹病毒（HVT）在抗原性上相似，但其在Tm为24.4摄氏度时的DNA序列与HVT仅有0.3 - 0.6%的同源性。在严格条件下的Southern印迹杂交表明，MDV与HVT之间的同源性位于这些病毒基因组的受限部分。在Tm为49.6摄氏度时，这允许检测MDV和HVT DNA之间每三个碱基中有一个错配的同源性，发现弱同源性序列分布在这些病毒基因组的大部分区域。在爱泼斯坦 - 巴尔病毒与MDV或HVT DNA之间未检测到同源性。

相似文献

1
Evaluation of DNA homology of Marek's disease virus, herpesvirus of turkeys and Epstein-Barr virus under varied stringent hybridization conditions.在不同严格杂交条件下对马立克氏病病毒、火鸡疱疹病毒和爱泼斯坦-巴尔病毒的DNA同源性评估。
J Biochem. 1984 Apr;95(4):1215-8. doi: 10.1093/oxfordjournals.jbchem.a134712.
2
Gene sequence and mapping data from Marek's disease virus and herpesvirus of turkeys: implications for herpesvirus classification.来自马立克氏病病毒和火鸡疱疹病毒的基因序列及图谱数据：对疱疹病毒分类的意义
J Gen Virol. 1988 Aug;69 ( Pt 8):2033-42. doi: 10.1099/0022-1317-69-8-2033.
3
Similarities and dissimilarities in the structure and expression of viral genomes of various virus strains immunologically related to Marek's disease virus.与马立克氏病病毒免疫相关的各种病毒株的病毒基因组在结构和表达上的异同。
Arch Virol. 1986;89(1-4):113-30. doi: 10.1007/BF01309883.
4
Extensive homology exists between Marek disease herpesvirus and its vaccine virus, herpesvirus of turkeys.马立克氏病疱疹病毒与其疫苗病毒火鸡疱疹病毒之间存在广泛的同源性。
Proc Natl Acad Sci U S A. 1984 Jun;81(11):3365-9. doi: 10.1073/pnas.81.11.3365.
5
Characterization of the gene encoding herpesvirus of turkeys gp57-65: comparison to Marek's disease virus gp57-65 and herpes simplex virus glycoprotein C.火鸡疱疹病毒gp57-65编码基因的特性：与马立克氏病病毒gp57-65及单纯疱疹病毒糖蛋白C的比较
Virus Genes. 1990 Apr;3(4):291-307. doi: 10.1007/BF00569037.
6
Comparative studies on Marek's disease virus and herpesvirus of turkey DNAs.马立克氏病病毒与火鸡疱疹病毒DNA的比较研究。
J Gen Virol. 1979 Oct;45(1):119-31. doi: 10.1099/0022-1317-45-1-119.
7
Map location of homologous regions between Marek's disease virus and herpesvirus of turkey and the absence of detectable homology in the putative tumor-inducing gene.马立克氏病病毒与火鸡疱疹病毒同源区域的图谱定位以及假定的肿瘤诱导基因中未检测到的同源性
J Virol. 1985 Mar;53(3):994-7. doi: 10.1128/JVI.53.3.994-997.1985.
8
Latency of herpesvirus of turkey and Marek's disease virus genomes in a chicken T-lymphoblastoid cell line.火鸡疱疹病毒和马立克氏病病毒基因组在鸡T淋巴细胞系中的潜伏情况。
J Gen Virol. 1981 Mar;53(Pt 1):133-43. doi: 10.1099/0022-1317-53-1-133.
9
Restriction enzyme map of herpesvirus of turkey DNA and its collinear relationship with Marek's disease virus DNA.火鸡疱疹病毒DNA的限制性酶切图谱及其与马立克氏病病毒DNA的共线性关系。
Virology. 1987 Apr;157(2):351-8. doi: 10.1016/0042-6822(87)90277-7.
10
Homologies between herpesvirus of turkey and Marek's disease virus type-1 DNAs within two co-linearly arranged open reading frames, one encoding glycoprotein A.火鸡疱疹病毒与1型马立克氏病病毒DNA在两个共线性排列的开放阅读框内的同源性，其中一个编码糖蛋白A。
Gene. 1989 Dec 14;84(2):399-405. doi: 10.1016/0378-1119(89)90514-3.

引用本文的文献

1
Identification of a potential Marek's disease virus serotype 2 glycoprotein D gene with homology to herpes simplex virus glycoprotein D.鉴定出一种与单纯疱疹病毒糖蛋白D具有同源性的潜在马立克氏病病毒2型糖蛋白D基因。
Arch Virol. 1996;141(11):2207-16. doi: 10.1007/BF01718226.
2
Studies on the serological cross-reaction between Marek's disease virus and herpesvirus of turkeys using monoclonal antibodies to major virus-specific polypeptides. Brief report.利用针对主要病毒特异性多肽的单克隆抗体对马立克氏病病毒和火鸡疱疹病毒之间血清学交叉反应的研究。简报
Arch Virol. 1984;81(3-4):337-43. doi: 10.1007/BF01310004.
3
A comparison of the biological properties of type 2 plaque-producing agent derived from the Cal-1 strain of Marek's disease virus with other related viruses.
源自马立克氏病病毒Cal-1株的2型致斑块剂与其他相关病毒生物学特性的比较。
Arch Virol. 1986;89(1-4):29-43. doi: 10.1007/BF01309877.
4
Map location of homologous regions between Marek's disease virus and herpesvirus of turkey and the absence of detectable homology in the putative tumor-inducing gene.马立克氏病病毒与火鸡疱疹病毒同源区域的图谱定位以及假定的肿瘤诱导基因中未检测到的同源性
J Virol. 1985 Mar;53(3):994-7. doi: 10.1128/JVI.53.3.994-997.1985.
5
RNA transcripts of Marek's disease virus (MDV) serotype-1 in infected and transformed cells.感染及转化细胞中1型马立克氏病病毒（MDV）的RNA转录本
Virus Genes. 1988 Oct;2(1):49-68. doi: 10.1007/BF00569736.
6
Similarities and dissimilarities in the structure and expression of viral genomes of various virus strains immunologically related to Marek's disease virus.与马立克氏病病毒免疫相关的各种病毒株的病毒基因组在结构和表达上的异同。
Arch Virol. 1986;89(1-4):113-30. doi: 10.1007/BF01309883.
7
Replicating Marek's disease virus (MDV) serotype 2 DNA with inserted MDV serotype 1 DNA sequences in a Marek's disease lymphoblastoid cell line MSB1-41C.在马立克氏病淋巴母细胞系MSB1-41C中复制插入了1型马立克氏病病毒（MDV）DNA序列的2型马立克氏病病毒（MDV）DNA。
Arch Virol. 1990;114(3-4):153-65. doi: 10.1007/BF01310745.
8
Immunological relationship between feline herpesvirus type 1 (FHV-1) and canine herpesvirus (CHV) as revealed by polyvalent and monoclonal antibodies.
Arch Virol. 1990;111(3-4):165-76. doi: 10.1007/BF01311051.
9
Identification of viral proteins encoded by two DNA fragments of herpesvirus of turkeys (HVT).火鸡疱疹病毒（HVT）两个DNA片段编码的病毒蛋白的鉴定
Virus Genes. 1991 Jul;5(3):227-33. doi: 10.1007/BF00568972.