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P物质对含促肾上腺皮质激素的下丘脑神经元的突触调节。

Synaptic regulation of hypothalamic neurons containing ACTH by substance P.

作者信息

Hisano S, Okamura Y, Daikoku S

出版信息

Brain Res. 1984 Aug 6;308(1):162-5. doi: 10.1016/0006-8993(84)90930-2.

Abstract

Synaptic connections between substance P (SP)- and ACTH-containing neurons in the rat arcuate nucleus were studied by a technique of combined pre- and postembedding immunohistochemical staining. The results showed that immunoreactive (ir) SP fiber terminals form synapses with ir ACTH cell bodies. This strongly suggests that the activity of ACTH neurons is under neuronal regulation by SP neurons.

摘要

采用包埋前和包埋后免疫组织化学染色相结合的技术,研究了大鼠弓状核中含P物质(SP)和促肾上腺皮质激素(ACTH)的神经元之间的突触连接。结果显示,免疫反应性(ir)SP纤维终末与ir ACTH细胞体形成突触。这有力地表明,ACTH神经元的活动受SP神经元的神经调节。

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