Miller D C, Goodman M L, Pilch B Z, Shi S R, Dickersin G R, Halpern H, Norris C M
Cancer. 1984 Nov 1;54(9):2019-28. doi: 10.1002/1097-0142(19841101)54:9<2019::aid-cncr2820540940>3.0.co;2-p.
Two cases of olfactory neuroblastoma mixed with other neoplastic elements are reported. One tumor contained foci of adenocarcinoma and of ganglioneuroblastoma in addition to an undifferentiated small cell component consistent with neuroblastoma; the other tumor histologically resembled small cell undifferentiated carcinoma with foci of squamous differentiation, but was shown by electron microscopy to be neuroblastoma. The histogenesis and treatment of mixed tumors of this type are discussed.
报告了两例伴有其他肿瘤成分的嗅神经母细胞瘤。其中一例肿瘤除了含有与神经母细胞瘤一致的未分化小细胞成分外,还包含腺癌和神经节神经母细胞瘤灶;另一例肿瘤在组织学上类似于伴有鳞状分化灶的小细胞未分化癌,但电镜检查显示为神经母细胞瘤。本文讨论了这类混合性肿瘤的组织发生及治疗。