Zverev Ia F, Belomestnykh V G
Farmakol Toksikol. 1984 Jul-Aug;47(4):86-8.
Experiments on rats have shown that administration of furosemide, dichlothiazide and etacrinic acid (50 mg/kg intraperitoneally) reduced the development of experimental inflammatory edema caused by subplantar administration of 0.1 ml of 6% dextran or 10% ovalbumin. The antiedematous effect of the diuretics was preserved under the conditions of bilateral nephrectomy, which points to the presence of extrarenal mechanisms in the action of the drugs in experimental inflammation.
对大鼠的实验表明，腹腔注射速尿、双氢氯噻嗪和依他尼酸（50毫克/千克）可减轻因足底注射0.1毫升6%右旋糖酐或10%卵清蛋白所致实验性炎性水肿的发展。在双侧肾切除的情况下，利尿剂的抗水肿作用依然存在，这表明这些药物在实验性炎症中的作用存在肾外机制。
