Leucht W, Cremer M, Felder K D, Schmidt W
Geburtshilfe Frauenheilkd. 1984 Aug;44(8):533-6. doi: 10.1055/s-2008-1036714.
If, in twin pregnancy, one twin shows severe malformation, the question arises as to how the other twin can remain unaffected. For the purpose of ensuring the diagnosis in case of suspected neural tube defect, the main diagnostic tools are sonography, biochemical methods of alpha-fetoprotein determination and acetyl cholinesterase activity, as well as cell-morphological identification of so-called "rapidly adhering cells". Parents and obstetricians face a difficult decision when confronted by the possibilities of maintaining pregnancy or of induced abortion after diagnosis of a malformed and a healthy twin. The case of a severe discordant cranial malformation is described on the basis of a case report. The diagnostic and therapeutic problems are discussed.
在双胎妊娠中，如果一个胎儿出现严重畸形，就会产生另一个胎儿为何能不受影响的问题。为了在怀疑神经管缺陷时确保诊断，主要的诊断工具包括超声检查、甲胎蛋白测定和乙酰胆碱酯酶活性的生化方法，以及所谓“快速黏附细胞”的细胞形态学鉴定。在诊断出一个畸形胎儿和一个健康胎儿后，父母和产科医生在面临维持妊娠或人工流产的可能性时，会面临艰难的抉择。本文根据一例病例报告描述了严重不一致的颅骨畸形病例。并对诊断和治疗问题进行了讨论。
