Brodin B, Hesselvik F, von Schenck H
Scand J Clin Lab Invest. 1984 Oct;44(6):529-33. doi: 10.1080/00365518409083606.
Intravenous infusion of 500 ml of a gelatin-based plasma substitute, Haemaccel, given to healthy volunteers, resulted in a significant decrease of the immunoreactive plasma fibronectin concentration 48 h and 72 h after infusion. One hour after infusion, the ability of fibronectin to bind gelatin was inhibited with a gradual recovery within 48 h. A dextran based plasma substitute, Macrodex, did not have this effect on plasma fibronectin.
给健康志愿者静脉输注500毫升明胶基血浆代用品贺斯，输注后48小时和72小时免疫反应性血浆纤连蛋白浓度显著降低。输注1小时后，纤连蛋白与明胶结合的能力受到抑制，48小时内逐渐恢复。葡聚糖基血浆代用品右旋糖酐对血浆纤连蛋白没有这种作用。
