Prognostic value of DNA histograms of bone marrow cells in acute myeloblastic leukaemias.

DNA histograms of bone marrow cells were studied in 25 patients with acute myeloblastic leukemia before starting treatment. It was found that patients with complete remission showed a significantly higher proportion of cells in phase S of the cellular cycle (22 +/- 3%) than patients who failed to achieve remission (12 +/- 4%). Assessment of DNA histograms of bone marrow cells may be one of prognostic factors in acute myeloblastic leukemia.