一名健康同性恋男子精液和血液中的人类嗜T淋巴细胞病毒III型

HTLV-III in the semen and blood of a healthy homosexual man.

作者信息

Ho D D, Schooley R T, Rota T R, Kaplan J C, Flynn T, Salahuddin S Z, Gonda M A, Hirsch M S

出版信息

Science. 1984 Oct 26;226(4673):451-3. doi: 10.1126/science.6208608.

DOI:10.1126/science.6208608

PMID:6208608

Abstract

Human T-lymphotropic virus type III (HTLV-III) is the probable etiologic agent for the acquired immune deficiency syndrome (AIDS). HTLV-III was isolated from semen and blood of a healthy homosexual man whose serum contains antibodies to HTLV-III. The finding of virus in semen supports epidemiologic data that suggest that AIDS can be transmitted sexually. In addition, the demonstration of HTLV-III in the blood and semen of a healthy individual establishes an asymptomatic, virus-positive carrier state which may be important in the dissemination of HTLV-III and, consequently, AIDS.

摘要

人类嗜T淋巴细胞病毒III型（HTLV - III）可能是获得性免疫缺陷综合征（艾滋病）的病原体。HTLV - III是从一名健康同性恋男性的精液和血液中分离出来的，其血清中含有抗HTLV - III抗体。在精液中发现该病毒支持了艾滋病可通过性传播的流行病学数据。此外，在一名健康个体的血液和精液中检测到HTLV - III，确立了一种无症状的病毒阳性携带者状态，这可能在HTLV - III的传播以及随之而来的艾滋病传播中具有重要意义。