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重症急性胰腺炎的腹腔灌洗

Peritoneal lavage in severe acute pancreatitis.

作者信息

Lasson A, Balldin G, Genell S, Ohlsson K

出版信息

Acta Chir Scand. 1984;150(6):479-84.

PMID:6208711
Abstract

An analysis is presented of 73 attacks of acute pancreatitis treated with non-operative peritoneal lavage, classified according to Ranson's 11 signs and followed up for on average four years. None of the 21 moderate attacks was associated with complications or mortality. In the 52 severe attacks, four patients (7.7%) died, new pseudocyst developed in five patients (9.6%) and abscess in four (7.7%), and diabetes was found in 12 patients (23%) at follow-up. In all these respects the severe attacks showed statistically significant difference from the moderate attacks, as did the need for assisted ventilation, the volume of gastric retention and the length of hospital stay. The authors conclude that non-operative peritoneal lavage is beneficial, probably by removing toxic substances from the peritoneal cavity.

摘要

本文对73例采用非手术性腹腔灌洗治疗的急性胰腺炎发作病例进行了分析,这些病例根据兰森(Ranson)的11项体征进行分类,并平均随访了4年。21例中度发作病例均未出现并发症或死亡。在52例重度发作病例中,4例患者(7.7%)死亡,5例患者(9.6%)出现新的假性囊肿,4例患者(7.7%)出现脓肿,随访时发现12例患者(23%)患有糖尿病。在所有这些方面,重度发作与中度发作相比均显示出统计学上的显著差异,辅助通气的需求、胃潴留量和住院时间也是如此。作者得出结论,非手术性腹腔灌洗是有益的,可能是通过清除腹腔内的有毒物质。

相似文献

1
Peritoneal lavage in severe acute pancreatitis.重症急性胰腺炎的腹腔灌洗
Acta Chir Scand. 1984;150(6):479-84.
2
Early prediction of severity of acute pancreatitis using peritoneal lavage.
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3
[Treatment of acute necrotizing pancreatitis with peritoneal lavage. 12 cases].
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6
[Necrosectomy and retroperitoneal lavage in necrotic pancreatitis].
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Surg Infect (Larchmt). 2006;7 Suppl 2:S113-6. doi: 10.1089/sur.2006.7.s2-113.

引用本文的文献

1
Pancreatic resection versus peritoneal lavage in acute necrotizing pancreatitis. A prospective randomized trial.急性坏死性胰腺炎中行胰腺切除术与腹腔灌洗术的比较:一项前瞻性随机试验
Ann Surg. 1991 Dec;214(6):663-6. doi: 10.1097/00000658-199112000-00004.
2
Pancreatic surgery, not pancreatitis, is the primary cause of diabetes after acute fulminant pancreatitis.胰腺手术而非胰腺炎,是急性暴发性胰腺炎后糖尿病的主要病因。
Gut. 1992 Jun;33(6):843-7. doi: 10.1136/gut.33.6.843.
3
Fibrinolytic enzymes in ascites during experimental acute pancreatitis in rats.
大鼠实验性急性胰腺炎腹水内的纤溶酶
Int J Pancreatol. 1992 Oct;12(2):127-37. doi: 10.1007/BF02924636.
4
Effective peritoneal therapy of acute pancreatitis in the rat with glutaryl-trialanin-ethylamide: a novel inhibitor of pancreatic elastase.用戊二酰 - 丙氨酰 - 乙酰胺对大鼠急性胰腺炎进行有效的腹膜治疗:一种新型胰弹性蛋白酶抑制剂。
Gut. 1992 May;33(5):701-6. doi: 10.1136/gut.33.5.701.