脾切除术对单核细胞增生李斯特菌感染小鼠中干扰素和集落刺激因子产生的影响。
Effect of splenectomy on production of interferon and colony-stimulating factor in Listeria monocytogenes-infected mice.
作者信息
Wood P R, Young A M, McKimm-Breschkin J L, Cheers C
出版信息
Infect Immun. 1984 Dec;46(3):860-1. doi: 10.1128/iai.46.3.860-861.1984.
Abstract
Splenectomy of mice genetically susceptible to Listeria monocytogenes genetically susceptible mouse strains increased their resistance to L. monocytogenes infection but had no effect on the course of infection in L. monocytogenes-resistant mice. However, splenectomy led to a dramatic decrease in the production of colony-stimulating factor and interferon after L. monocytogenes infection in all mouse strains examined.
摘要
对单核细胞增生李斯特菌遗传易感性小鼠品系进行脾切除，可增强其对单核细胞增生李斯特菌感染的抵抗力，但对单核细胞增生李斯特菌抗性小鼠的感染进程没有影响。然而，在所有检测的小鼠品系中，脾切除导致单核细胞增生李斯特菌感染后集落刺激因子和干扰素的产生显著减少。
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