Fåhraeus T, Lassvik C, Sonnhag C
Pacing Clin Electrophysiol. 1984 Nov;7(6 Pt 1):1049-54. doi: 10.1111/j.1540-8159.1984.tb05656.x.
Available automatic tachycardia-terminating pacemakers cannot distinguish between physiological and pathological tachycardia and, consequently, electrical stimulation during sinus tachycardia can occur. In order to evaluate whether this might be an arrhythmogenic problem or not, the cardiac response in eight patients having paroxysmal supraventricular tachycardia treated with tachycardia-terminating pacemakers was studied during exercise. After tachycardia recognition, the implanted pulse generator automatically emits single or double critically timed premature stimuli for termination of the arrhythmia. Post-implantation examinations revealed successful tachycardia termination by the pacemaker at rest, without the addition of any antiarrhythmic drugs, in all eight patients. During exercise tests, the sinus rate in seven patients exceeded the programmed tachycardia trigger rate resulting in triggered pacemaker stimulation. The native supraventricular tachycardia was initiated in four cases. In one of these patients, two short episodes of probable ventricular tachycardia were also recorded. This study demonstrates the clinical value of post-implantation assessments with exercise tests concerning the problem of pacemaker-initiated tachyarrhythmias. Tachycardia-terminating devices can induce tachycardias, and individual precautions must be taken in order to prevent or minimize the risk of pacemaker reversion of sinus rhythm to paroxysmal tachycardia or hazardous arrhythmias.
现有的自动终止心动过速起搏器无法区分生理性和病理性心动过速,因此,在窦性心动过速期间可能会发生电刺激。为了评估这是否可能是一个致心律失常的问题,对8例接受终止心动过速起搏器治疗的阵发性室上性心动过速患者在运动期间的心脏反应进行了研究。在识别出心动过速后,植入的脉冲发生器会自动发出单次或两次关键定时的过早刺激以终止心律失常。植入后检查显示,在未添加任何抗心律失常药物的情况下,所有8例患者的起搏器在静息时均成功终止了心动过速。在运动测试期间,7例患者的窦性心律超过了程控的心动过速触发率,导致起搏器触发刺激。4例患者诱发了原有的室上性心动过速。在其中1例患者中,还记录到了2次短暂的疑似室性心动过速发作。这项研究证明了运动测试植入后评估对于起搏器诱发的心律失常问题的临床价值。终止心动过速的装置可能会诱发心动过速,必须采取个体预防措施以防止或最小化起搏器将窦性心律逆转为阵发性心动过速或危险心律失常的风险。