Fearnot N E, Jolgren D L, Tacker W A, Nelson J P, Geddes L A
Pacing Clin Electrophysiol. 1984 Nov;7(6 Pt 2):1240-5. doi: 10.1111/j.1540-8159.1984.tb05690.x.
A pacemaker that increases pacing rate in response to exercise enables the pacemaker patient to improve his state of well-being. Possible sensors include atrial rate, Q-T interval, pH, venous oxygen saturation, respiratory rate, cardiac output, body motion, and blood temperature. To determine the efficacy of right ventricular blood temperature as an indicator of exercise, an experimental temperature-controlled pacemaker was developed and was evaluated in dogs. A resulting algorithm was implemented in a microcomputer-based VVI pacemaker which reliably detected exercise and rest from blood temperature when totally implanted. The pacemaker generated two pacing rates to provide increased cardiac output. Data is being obtained to establish feasibility in humans.
一种能根据运动增加起搏频率的起搏器可使起搏器患者改善其健康状况。可能的传感器包括心房率、Q-T间期、pH值、静脉血氧饱和度、呼吸频率、心输出量、身体运动和体温。为了确定右心室血温作为运动指标的有效性，开发了一种实验性温度控制起搏器并在狗身上进行了评估。由此产生的算法被应用于基于微型计算机的VVI起搏器中，该起搏器在完全植入时能可靠地根据血温检测运动和休息状态。该起搏器产生两种起搏频率以增加心输出量。目前正在获取数据以确定其在人体中的可行性。
