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妊娠相关血浆蛋白A在蜕膜和滋养层中的免疫组织化学定位：与人类绒毛膜促性腺激素和纤维蛋白的比较

Immunohistochemical localization of pregnancy-associated plasma protein A in decidua and trophoblast: comparison with human chorionic gonadotrophin and fibrin.

作者信息

Schindler A M, Bordignon P, Bischof P

出版信息

Placenta. 1984 May-Jun;5(3):227-35. doi: 10.1016/s0143-4004(84)80032-6.

DOI:10.1016/s0143-4004(84)80032-6
PMID:6209703
Abstract

In an immunoperoxidase study, pregnancy-associated placental protein A (PAPP-A) was localized to the cytoplasm of decidual stromal cells, the villous syncytiotrophoblast and on the surface of placental trophoblast. A decidual and a trophoblastic origin is suggested for PAPP-A, and its presence on the surface of the syncytiotrophoblast is interpreted as a possible immunoprotective layer.

摘要

在一项免疫过氧化物酶研究中，妊娠相关胎盘蛋白A（PAPP-A）定位于蜕膜基质细胞、绒毛合体滋养层细胞的细胞质以及胎盘滋养层表面。提示PAPP-A起源于蜕膜和滋养层，其在合体滋养层表面的存在被解释为可能是一层免疫保护层。

相似文献

1
Immunohistochemical localization of pregnancy-associated plasma protein A in decidua and trophoblast: comparison with human chorionic gonadotrophin and fibrin.妊娠相关血浆蛋白A在蜕膜和滋养层中的免疫组织化学定位：与人类绒毛膜促性腺激素和纤维蛋白的比较
Placenta. 1984 May-Jun;5(3):227-35. doi: 10.1016/s0143-4004(84)80032-6.
2
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Gynecol Obstet Invest. 1987;23(2):97-102. doi: 10.1159/000298842.
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Am J Obstet Gynecol. 1989 Aug;161(2):446-53. doi: 10.1016/0002-9378(89)90540-1.
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Dynamic changes in hyperglycosylated human chorionic gonadotrophin throughout the first trimester of pregnancy and its role in early placentation.孕期早期高糖基化人绒毛膜促性腺激素的动态变化及其在早期胎盘形成中的作用。
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Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, biochemical and functional features.中间型滋养细胞：一种具有特定形态、生化和功能特征的独特滋养细胞形式。
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Immunohistochemical localization of pregnancy-associated plasma protein A (PAPP-A) in placentae from normal and pre-eclamptic pregnancies.妊娠相关血浆蛋白A（PAPP-A）在正常妊娠和子痫前期妊娠胎盘组织中的免疫组化定位
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Comparative study of placental protein 19, human chorionic gonadotrophin and pregnancy-specific beta 1-glycoprotein as immunohistochemical markers for extravillous trophoblast in pregnancy and trophoblastic disease.胎盘蛋白19、人绒毛膜促性腺激素和妊娠特异性β1-糖蛋白作为妊娠和滋养细胞疾病中外周滋养细胞免疫组化标志物的比较研究。
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[Immunohistochemical localization of hCG alpha, hCG beta CTP, hPL and SP1 on villous and extravillous trophoblasts in normal human pregnancy].[人正常妊娠时绒毛和绒毛外滋养层细胞中hCGα、hCGβ CTP、hPL和SP1的免疫组织化学定位]
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引用本文的文献

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Int J Mol Sci. 2023 Apr 21;24(8):7669. doi: 10.3390/ijms24087669.
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Noninvasive detection of trophoblast protein signatures linked to early pregnancy loss using trophoblast retrieval and isolation from the cervix (TRIC).使用从宫颈中获取和分离滋养层细胞（TRIC）的方法对与早期妊娠丢失相关的滋养层蛋白特征进行无创检测。
Fertil Steril. 2015 Aug;104(2):339-46.e4. doi: 10.1016/j.fertnstert.2015.05.010. Epub 2015 Jun 11.
3
Pattern of secretion of pregnancy-associated plasma protein-A (PAPP-A) during pregnancies complicated by fetal aneuploidy, in vivo and in vitro.
孕期合并胎儿非整倍体时妊娠相关血浆蛋白-A（PAPP-A）的体内外分泌模式
Reprod Biol Endocrinol. 2014 Dec 28;12:129. doi: 10.1186/1477-7827-12-129.
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A sensitive enzyme immunoassay for pregnancy-associated plasma protein A (PAPP-A): a possible first trimester method of screening for Down syndrome and other trisomies.一种用于妊娠相关血浆蛋白A（PAPP-A）的灵敏酶免疫测定法：一种可能的孕早期唐氏综合征及其他三体综合征筛查方法。
Arch Gynecol Obstet. 1995;256(4):185-92. doi: 10.1007/BF00634490.
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Histochem J. 1986 Apr;18(4):184-8. doi: 10.1007/BF01676119.
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