Kurman R J, Main C S, Chen H C
Placenta. 1984 Jul-Aug;5(4):349-69. doi: 10.1016/s0143-4004(84)80015-6.
Morphological and immunohistochemical analysis of placental tissue from 12 days to term using antibodies directed against the unique carboxyl terminal peptide of human chorionic gonadotrophin beta subunit, human placental lactogen (hPL) and pregnancy-specific beta I-glycoprotein reveals that an intermediate form of trophoblast with distinctive features exists. This cell has a diverse morphological expression and is located overlying chorionic villi, in the trophoblastic columns, basal plate and the trophoblastic shell. Although all three placental proteins are localized in this cell the predominant hormone is hPL, which can serve as an immunocytochemical marker. One of the primary functions of this cell is in implantation and in the establishment of the uteroplacental circulation since it extensively invades the spiral arteries at the placental site. It is proposed that this distinctive form of trophoblast be termed 'intermediate trophoblast'.
使用针对人绒毛膜促性腺激素β亚基独特羧基末端肽、人胎盘催乳素(hPL)和妊娠特异性βI -糖蛋白的抗体,对从12天到足月的胎盘组织进行形态学和免疫组织化学分析,结果显示存在一种具有独特特征的中间型滋养层细胞。这种细胞具有多样的形态学表现,位于绒毛膜绒毛上方、滋养层柱、基底板和滋养层壳中。尽管这三种胎盘蛋白都定位于这种细胞中,但主要的激素是hPL,它可作为免疫细胞化学标记物。这种细胞的主要功能之一是参与着床和子宫胎盘循环的建立,因为它会广泛侵入胎盘部位的螺旋动脉。有人提出将这种独特形式的滋养层细胞称为“中间型滋养层细胞”。