Lababidi Z A, Daskalopoulos D A, Stoeckle H
Am J Cardiol. 1984 Dec 1;54(10):1288-91. doi: 10.1016/s0002-9149(84)80083-1.
Transluminal balloon angioplasty (BA) was performed in 27 consecutive patients with coarctation of the aorta (COA), including 7 infants with preductal COA, 7 patients with restenosed COA after surgical repair, and 13 older children and 1 adult with unoperated COA. The patients were 4 days to 27 years old. The balloon was positioned across the COA and inflated sequentially to pressures of 100 and 120 psi, each inflation lasting for 5 to 10 seconds. Peak systolic pressure gradient (PSG) across the COA was recorded and an aortogram was performed before and immediately after BA. PSG also was recorded during follow-up studies performed in 13 patients 3 to 24 months after BA. BA was performed without complications in each patient. Immediately after BA, the mean PSG was reduced from 49 +/- 21 to 10 +/- 7 mm Hg (p less than 0.01), and the mean COA diameter increased from 3.9 +/- 1.4 to 9.6 +/- 3.6 mm (p less than 0.01). After a follow-up period of 3 to 24 months, the mean PSG remained low (15 +/- 11 mm Hg) and the mean COA diameter increased to 10.5 +/- 4.6 mm. BA can be performed safely. It can be a useful palliative treatment in seriously ill infants with COA.
对27例连续性主动脉缩窄（COA）患者进行了腔内球囊血管成形术（BA），其中包括7例导管前型COA婴儿、7例手术修复后COA再狭窄患者、13例大龄儿童和1例未接受手术的COA成人。患者年龄从4天至27岁不等。将球囊置于COA部位并依次充压至100和120磅力/平方英寸，每次充气持续5至10秒。记录COA两端的收缩期峰值压力梯度（PSG），并在BA术前和术后即刻进行主动脉造影。在BA术后3至24个月对13例患者进行随访研究时也记录PSG。每位患者BA手术均无并发症发生。BA术后即刻，平均PSG从49±21降至10±7毫米汞柱（p<0.01），平均COA直径从3.9±1.4增加至9.6±3.6毫米（p<0.01）。经过3至24个月的随访期，平均PSG仍保持较低水平（15±11毫米汞柱），平均COA直径增加至10.5±4.6毫米。BA手术可安全实施。对于患有COA的重症婴儿，它可以是一种有效的姑息治疗方法。
