Rush J A, Older J J
J Clin Neuroophthalmol. 1981 Sep;1(3):219-24. doi: 10.3109/01658108109004922.
The value of the thyrotropin-releasing hormone (TRH) test may be insufficiently emphasized in the diagnosis of patients with euthyroid Graves' disease who have unexplained proptosis or vertical diplopia. We saw three patients who had these orbital symptoms and normal routine serum thyroid studies. The orbital computed tomograms (CT) found an orbital myopathy in all, and the diagnosis of Graves' orbitopathy was made by an abnormal TRH test. Not all euthyroid Graves' patients will show a positive result, but in those who do, the test is diagnostic. The clinical summaries of our three patients and the applications of the thyrotropin-releasing hormone test in ophthalmic practice are reviewed.
促甲状腺激素释放激素（TRH）试验在诊断患有原因不明的突眼或垂直性复视的甲状腺功能正常的格雷夫斯病患者中的价值可能未得到充分重视。我们见到了三名有这些眼眶症状且常规血清甲状腺检查正常的患者。眼眶计算机断层扫描（CT）显示他们均有眼眶肌病，通过异常的TRH试验确诊为格雷夫斯眼眶病。并非所有甲状腺功能正常的格雷夫斯病患者都会出现阳性结果，但对于出现阳性结果的患者，该试验具有诊断意义。本文回顾了我们三名患者的临床摘要以及促甲状腺激素释放激素试验在眼科实践中的应用。
