Osterman K, Zetterström O, Johansson S G
Allergy. 1982 Jul;37(5):313-22. doi: 10.1111/j.1398-9995.1982.tb01917.x.
Workers in the coffee industry were investigated. Study I comprised 50 selected cases of whom 25 had work-related symptoms and 25 had not. Prick tests and RAST investigations with different factory dust extracts were performed. Study II was a cross-sectional study comprising 129 workers who were prick-tested with one factory dust extract and with castor bean (CB). More than 40% described occupationally related asthma, rhinitis, conjunctivitis or pruritus, and in about half of these cases sensitization with one or two allergens was found. One allergen comes from coffee beans and is found in the factory dust, mainly where the raw coffee is handled. This allergen is destroyed in the roasting process. The other allergen is identical with the allergen from castor bean and its presumed to enter the plant via the sacks. Predisposing factors to developing sensitization were atopic status, degree and length of exposure, and smoking habits.
对咖啡行业的工人进行了调查。研究I选取了50个病例，其中25人有与工作相关的症状，25人没有。用不同的工厂粉尘提取物进行了点刺试验和RAST检测。研究II是一项横断面研究，包括129名工人，用一种工厂粉尘提取物和蓖麻子（CB）进行点刺试验。超过40%的人描述有职业性哮喘、鼻炎、结膜炎或瘙痒，在这些病例中，约一半发现对一种或两种过敏原致敏。一种过敏原来自咖啡豆，存在于工厂粉尘中，主要在处理生咖啡的地方。这种过敏原在烘焙过程中被破坏。另一种过敏原与蓖麻子中的过敏原相同，推测是通过麻袋进入工厂的。发生致敏的易感因素包括特应性状态、接触程度和时长以及吸烟习惯。
