• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用从大鼠肝脏染色质中分离出的酶切除DNA中的脱嘌呤位点。

Excision of apurinic sites from DNA with enzymes isolated from rat-liver chromatin.

作者信息

Goffin C, Verly W G

出版信息

Eur J Biochem. 1982 Oct;127(3):619-23. doi: 10.1111/j.1432-1033.1982.tb06917.x.

DOI:10.1111/j.1432-1033.1982.tb06917.x
PMID:6217070
Abstract

Apurinic sites were excised from phi X174 RF DNA with two enzymes isolated from rat liver chromatin: an apurinic/apyrimidinic endodeoxyribonuclease and a 5'-3'-exonuclease; the resulting gap was filled with DNA polymerase beta also prepared from rat liver chromatin and the repair was fully terminated with T4 ligase.

摘要

用从大鼠肝脏染色质中分离出的两种酶从噬菌体X174环形双链DNA上去除脱嘌呤位点：一种脱嘌呤/脱嘧啶内切脱氧核糖核酸酶和一种5'-3'-外切核酸酶；产生的缺口用同样从大鼠肝脏染色质中制备的DNA聚合酶β填补，并用T4连接酶使修复完全终止。

相似文献

1
Excision of apurinic sites from DNA with enzymes isolated from rat-liver chromatin.用从大鼠肝脏染色质中分离出的酶切除DNA中的脱嘌呤位点。
Eur J Biochem. 1982 Oct;127(3):619-23. doi: 10.1111/j.1432-1033.1982.tb06917.x.
2
Repair of depurinated DNA with enzymes from rat liver chromatin.用大鼠肝脏染色质中的酶修复脱嘌呤DNA。
Biochem J. 1984 May 15;220(1):133-7. doi: 10.1042/bj2200133.
3
Intranucleosomal localization of the AP endodeoxyribonuclease of rat liver chromatin.
FEBS Lett. 1983 Jun 27;157(1):115-8. doi: 10.1016/0014-5793(83)81127-2.
4
The apurinic/apyrimidinic endodeoxyribonuclease of rat-liver chromatin.大鼠肝脏染色质的无嘌呤/无嘧啶内切脱氧核糖核酸酶
Eur J Biochem. 1983 Jan 1;129(3):509-17. doi: 10.1111/j.1432-1033.1983.tb07077.x.
5
Excision of apurinic and/or apyrimidinic sites from DNA by nucleolytical enzymes from rat brain.
Eur J Biochem. 1988 Feb 15;172(1):155-9. doi: 10.1111/j.1432-1033.1988.tb13867.x.
6
Localization of the phosphoester bond hydrolyzed by the major apurinic/apyrmidinic endodeoxyribonuclease from rat-liver chromatin.
Eur J Biochem. 1981 Aug;118(1):195-201. doi: 10.1111/j.1432-1033.1981.tb05505.x.
7
Possible roles of beta-elimination and delta-elimination reactions in the repair of DNA containing AP (apurinic/apyrimidinic) sites in mammalian cells.β-消除反应和δ-消除反应在哺乳动物细胞中含AP（脱嘌呤/脱嘧啶）位点的DNA修复中的可能作用。
Biochem J. 1988 Jul 15;253(2):553-9. doi: 10.1042/bj2530553.
8
Purification and properties of the major apurinic/apyrimidinic endodeoxyribonuclease of rat-liver chromatin.大鼠肝脏染色质主要脱嘌呤/脱嘧啶内切脱氧核糖核酸酶的纯化及性质
Eur J Biochem. 1980 Sep;110(2):379-85. doi: 10.1111/j.1432-1033.1980.tb04878.x.
9
Purification and some properties of apurinic/apyrimidinic DNA endonucleases in rat liver.
Int J Biochem. 1993 Dec;25(12):1925-33. doi: 10.1016/0020-711x(88)90326-6.
10
Cellular localization of the apurinic/apyrimidinic endodeoxyribonucleases in rat liver.大鼠肝脏中脱嘌呤/脱嘧啶内切脱氧核糖核酸酶的细胞定位
Eur J Biochem. 1980 Jun;107(2):555-63. doi: 10.1111/j.1432-1033.1980.tb06063.x.

引用本文的文献

1
Repair of depurinated DNA with enzymes from rat liver chromatin.用大鼠肝脏染色质中的酶修复脱嘌呤DNA。
Biochem J. 1984 May 15;220(1):133-7. doi: 10.1042/bj2200133.
2
T4 DNA ligase can seal a nick in double-stranded DNA limited by a 5'-phosphorylated base-free deoxyribose residue.T4 DNA连接酶能够封闭双链DNA中由5'-磷酸化的无碱基脱氧核糖残基所限定的切口。
Nucleic Acids Res. 1983 Nov 25;11(22):8103-9. doi: 10.1093/nar/11.22.8103.
3
Deoxyribonuclease IV from rat liver chromatin and the excision of apurinic sites from depurinated DNA.
来自大鼠肝脏染色质的脱氧核糖核酸酶IV与脱嘌呤DNA中无嘌呤位点的切除
Biochem J. 1985 Jan 15;225(2):535-42. doi: 10.1042/bj2250535.
4
Delta-elimination in the repair of AP (apurinic/apyrimidinic) sites in DNA.DNA中脱嘌呤/脱嘧啶（AP）位点修复中的δ消除
Biochem J. 1989 Aug 1;261(3):707-13. doi: 10.1042/bj2610707.
5
The multiple activities of Escherichia coli endonuclease IV and the extreme lability of 5'-terminal base-free deoxyribose 5-phosphates.大肠杆菌核酸内切酶IV的多种活性以及5'-末端无碱基脱氧核糖5-磷酸的极度不稳定性。
Biochem J. 1989 May 1;259(3):761-8. doi: 10.1042/bj2590761.
6
Possible roles of beta-elimination and delta-elimination reactions in the repair of DNA containing AP (apurinic/apyrimidinic) sites in mammalian cells.β-消除反应和δ-消除反应在哺乳动物细胞中含AP（脱嘌呤/脱嘧啶）位点的DNA修复中的可能作用。
Biochem J. 1988 Jul 15;253(2):553-9. doi: 10.1042/bj2530553.