Aber G M, Higgins P M
Br J Urol. 1982 Dec;54(6):613-5. doi: 10.1111/j.1464-410x.1982.tb13607.x.
This is a rare, but potentially very troublesome disorder. We have been able to carry out detailed radiological, histological and biochemical investigations on 51 patients and the results of these investigations are presented. Considerable evidence of abnormal platelet activity has been found. The histological evidence has come from both biopsy and nephrectomy specimens and has shown aggressive atherosis leading to microembolic lesions and in some cases showing microaneurysm formation. In some instances this has led to areas of infarction both small and large. Most of the cases studied have been fully followed up and it has been found that despite the histological changes, the blood pressure remains normal and no demonstrable deterioration in renal function occurs. Attempts at treatment are described and discussed.
这是一种罕见但可能非常棘手的病症。我们已经对51例患者进行了详细的放射学、组织学和生化检查，并展示了这些检查的结果。已发现大量血小板活动异常的证据。组织学证据来自活检和肾切除标本，显示出侵袭性动脉粥样硬化导致微栓塞性病变，在某些情况下还显示出微动脉瘤形成。在某些情况下，这会导致大小不等的梗死区域。大多数研究病例都得到了充分随访，结果发现，尽管有组织学变化，但血压仍保持正常，肾功能也未出现明显恶化。文中描述并讨论了治疗尝试。
