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[大鼠的血小板、溶酶体酶与过敏性休克]

[Platelets, lysosomal enzymes and anaphylactic shock in the rat].

作者信息

Damas J, Bourdon V, Lecomte J, Salmon J

出版信息

C R Seances Soc Biol Fil. 1982;176(4):553-7.

PMID:6217876
Abstract
  1. Rat serum levels in beta-glucuronidase and beta-galactosidase are higher than plasma levels. Rat platelets release these lysosomial enzymes during blood coagulation in vitro. 2. After anaphylactic shock, in the sensitized rat, there is no increase in beta-galactosidase and beta-glucuronidase plasma levels. The tissues of the sensitized rat do not release these enzymes during the antigen-antibody reaction. The blood platelet level is diminished after anaphylactic shock and the serum levels of the lysosomial enzymes are decreased. 3. In thrombopenic rat, anaphylactic shock is identical as in control animals. Rat platelets do not play a significant role in the anaphylactic shock.
摘要
  1. 大鼠血清中β-葡萄糖醛酸酶和β-半乳糖苷酶的水平高于血浆水平。大鼠血小板在体外血液凝固过程中释放这些溶酶体酶。2. 在致敏大鼠发生过敏性休克后,血浆中β-半乳糖苷酶和β-葡萄糖醛酸酶水平没有升高。致敏大鼠的组织在抗原-抗体反应过程中不释放这些酶。过敏性休克后血小板水平降低,溶酶体酶的血清水平也降低。3. 在血小板减少的大鼠中,过敏性休克与对照动物相同。大鼠血小板在过敏性休克中不起重要作用。

相似文献

1
[Platelets, lysosomal enzymes and anaphylactic shock in the rat].[大鼠的血小板、溶酶体酶与过敏性休克]
C R Seances Soc Biol Fil. 1982;176(4):553-7.
2
Changes in the activity of certain lysosomal enzymes in the blood serum of rats subjected to whole body x-ray irradiation.
Acta Univ Carol Med Monogr. 1977(78 Pt 2):145-7.
3
Changes of the activity of certain lysosomal enzymes in the blood serum of whole-body irradiated rats.
Strahlentherapie. 1977 Jul;153(7):496-500.
4
Lysosomal enzyme activities in platelets of normal individuals and of patients with Gaucher's disease.正常个体及戈谢病患者血小板中的溶酶体酶活性。
Thromb Diath Haemorrh. 1974 Dec 31;32(2-3):665-9.
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Changes of the activity of acid phosphatase and beta-glucuronidase in isolated platelets of whole-body irradiated rats.全身照射大鼠分离血小板中酸性磷酸酶和β-葡萄糖醛酸酶活性的变化。
Strahlentherapie. 1983 Sep;159(9):584-9.
6
Lysosomal enzymes in human platelets.人类血小板中的溶酶体酶。
Cell Biochem Funct. 1985 Apr;3(2):121-5. doi: 10.1002/cbf.290030207.
7
Influence of age and sex on five human plasma lysosomal enzymes assayed by automated procedures.年龄和性别对通过自动化程序测定的五种人血浆溶酶体酶的影响。
Clin Chim Acta. 1981 Jun 18;113(2):141-52. doi: 10.1016/0009-8981(81)90148-0.
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Behaviour of several enzymes of lysosomal origin in human plasma during whole blood storage.
Clin Chim Acta. 1984 Nov 30;143(3):343-53. doi: 10.1016/0009-8981(84)90088-3.
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Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats.没食子酸可预防异丙肾上腺素诱导的Wistar大鼠心脏毒性中的溶酶体损伤。
Eur J Pharmacol. 2009 Aug 1;615(1-3):139-43. doi: 10.1016/j.ejphar.2009.05.003. Epub 2009 May 15.
10
Changes in the activity of certain lysosomal enzymes in the blood serum and organs of rats subjected to fractionated whole body irradiation with 60 CO.
Acta Univ Carol Med Monogr. 1977(78 Pt 2):149-53.

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