[大鼠的血小板、溶酶体酶与过敏性休克]
[Platelets, lysosomal enzymes and anaphylactic shock in the rat].
作者信息
Damas J, Bourdon V, Lecomte J, Salmon J
出版信息
C R Seances Soc Biol Fil. 1982;176(4):553-7.
PMID:6217876
Abstract
- Rat serum levels in beta-glucuronidase and beta-galactosidase are higher than plasma levels. Rat platelets release these lysosomial enzymes during blood coagulation in vitro. 2. After anaphylactic shock, in the sensitized rat, there is no increase in beta-galactosidase and beta-glucuronidase plasma levels. The tissues of the sensitized rat do not release these enzymes during the antigen-antibody reaction. The blood platelet level is diminished after anaphylactic shock and the serum levels of the lysosomial enzymes are decreased. 3. In thrombopenic rat, anaphylactic shock is identical as in control animals. Rat platelets do not play a significant role in the anaphylactic shock.
摘要
- 大鼠血清中β-葡萄糖醛酸酶和β-半乳糖苷酶的水平高于血浆水平。大鼠血小板在体外血液凝固过程中释放这些溶酶体酶。2. 在致敏大鼠发生过敏性休克后，血浆中β-半乳糖苷酶和β-葡萄糖醛酸酶水平没有升高。致敏大鼠的组织在抗原-抗体反应过程中不释放这些酶。过敏性休克后血小板水平降低，溶酶体酶的血清水平也降低。3. 在血小板减少的大鼠中，过敏性休克与对照动物相同。大鼠血小板在过敏性休克中不起重要作用。
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[Platelets, lysosomal enzymes and anaphylactic shock in the rat].[大鼠的血小板、溶酶体酶与过敏性休克]
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