Endo A, Hayashida O, Murakawa S
J Antibiot (Tokyo). 1983 Mar;36(3):203-7. doi: 10.7164/antibiotics.36.203.
Mutastein, a new inhibitor of glucosyltransferases (GTase) of Streptococcus mutans, was isolated from cultural broth of Aspergillus terreus M3328. Mutastein was a heat-stable protein and was sensitive to pronase digestion. In the formation of glucans, that of adhesive water-insoluble glucans of S. mutans was specifically inhibited by mutastein.
变链菌素是从土曲霉M3328的培养液中分离出的一种新型变形链球菌葡糖基转移酶（GTase）抑制剂。变链菌素是一种热稳定蛋白，对链霉蛋白酶消化敏感。在葡聚糖的形成过程中，变链菌素能特异性抑制变形链球菌粘性水不溶性葡聚糖的形成。
