Lashev L
Vet Med Nauki. 1982;19(8):65-72.
Determined were the serum concentrations of amoxicillin at the single and repeated oral administration to calves and pigs of the drug formula amopen-powder, containing 5 per cent amoxicillin tryhydrate. It was found that the resorption of the antibiotic was rapidly setting in, and there were high concentrations in the blood serum of the treated animals, in pigs both the resorption and the elimination of amoxicillin occurring at a higher rate. In calves with developed forestomach the antibiotic was resorbed twice slower than in sucking calves. In pigs the increase in feed with which the drug was offered resulted in its weaker resorption in the digestive tract.
测定了含有5%三水合阿莫西林的药物配方阿莫普粉对犊牛和仔猪单次及重复口服给药后的血清阿莫西林浓度。结果发现,抗生素的吸收迅速开始,治疗动物的血清中浓度较高,在仔猪中,阿莫西林的吸收和消除速率都较高。在前胃发达的犊牛中,抗生素的吸收速度比吮乳犊牛慢两倍。在仔猪中,添加药物的饲料增加导致其在消化道中的吸收减弱。