[Alterations in activity of the ATPase systems in subcellular fractions of brain and spinal cord in the preclinical period of botulinum poisoning].

Under conditions of the C type botulinic intoxication of rats blockade of cholinergic synaptic transmission and development of paralytic syndrome followed the distinct alteration in activity of the ATPase systems in various subcellular fractions of brain and spinal cord. This suggests that the toxin affects the various intracellular metabolic reactions related directly or indirectly to active transmembrane transport of ions.