Fóris G, Füst G, Medgyesi G A
Immunol Lett. 1983 Jan;6(1):7-11. doi: 10.1016/0165-2478(83)90022-6.
Effects of various substances known to influence macrophage functions on the adherence of C3b-coated sheep erythrocytes (E-C3b) and their phagocytosis by elicited rat peritoneal macrophages (PM) has been studied. Different oligopeptides (OP) having a chemotactic effect, such as tuftsin, angiotensin II (At II) and the OP-fraction of a lymphokine preparation (LK-OP) increased both adherence and phagocytosis of E-C3b in a concentration-dependent fashion. In contrast, neither substances influencing the membrane cation transport nor prostaglandins (PG) and cyclic nucleotides significantly changed the C3b receptor (C3bR)-dependent effector functions of macrophages. Enhanced functions of the C3bR were not associated with an increased capability of PMs for intracellular killing of Candida albicans.
研究了各种已知影响巨噬细胞功能的物质对C3b包被的绵羊红细胞（E-C3b）黏附以及对诱导的大鼠腹腔巨噬细胞（PM）吞噬作用的影响。具有趋化作用的不同寡肽（OP），如促吞噬素、血管紧张素II（At II）和一种淋巴因子制剂的OP组分（LK-OP），以浓度依赖方式增加了E-C3b的黏附和吞噬作用。相比之下，影响膜阳离子转运的物质、前列腺素（PG）和环核苷酸均未显著改变巨噬细胞依赖C3b受体（C3bR）的效应功能。C3bR功能增强与PM对白色念珠菌细胞内杀伤能力的增加无关。
