Githens S
J Histochem Cytochem. 1983 May;31(5):697-705. doi: 10.1177/31.5.6221048.
The light microscopic histochemical localization of alkaline phosphatase (APase) and adenosine triphosphatase (ATPase) in the mammalian pancreas is reviewed. Capillary endothelial cells usually exhibit both enzymes. ATPase is usually present in endocrine and acinar cells and absent in duct cells. APase is often found in islet cells but is almost always absent in exocrine cells. These enzymes should therefore be used with caution as markers for specific cells and organelles of the pancreas, and for monitoring diseases that might lead to the release of these enzymes from the pancreas.
本文综述了碱性磷酸酶(APase)和三磷酸腺苷酶(ATPase)在哺乳动物胰腺中的光镜组织化学定位。毛细血管内皮细胞通常同时显示这两种酶。ATPase通常存在于内分泌细胞和腺泡细胞中,而导管细胞中不存在。APase常出现在胰岛细胞中,但在外分泌细胞中几乎总是不存在。因此,在将这些酶用作胰腺特定细胞和细胞器的标志物以及监测可能导致这些酶从胰腺释放的疾病时应谨慎使用。