Cordoba O A, Chapel J L
Am J Psychiatry. 1983 Aug;140(8):1036-9. doi: 10.1176/ajp.140.8.1036.
A hypersexual pedophiliac sex offender was treated with the antiandrogen medroxyprogesterone acetate for 500 days. During the treatment, his testosterone blood levels significantly decreased, nearly to female values. Pituitary gonadotropin and urinary steroid metabolite levels diminished initially. Medroxyprogesterone therapy resulted in decreased libido, few side effects, and no recurrence of sex offenses, but there was no change in the patient's sexual orientation.
一名性欲亢进的恋童癖性犯罪者接受醋酸甲羟孕酮抗雄激素治疗500天。治疗期间，他的血液睾酮水平显著下降，几乎降至女性水平。垂体促性腺激素和尿类固醇代谢物水平最初有所降低。醋酸甲羟孕酮治疗导致性欲降低、副作用少且性犯罪未复发，但患者的性取向没有改变。
